![]() The most common sterilization methods mean that SAL 90%) relative humidity, resulting in > 3LOG 10 inactivation. For high-level disinfection and sterilization of semi-critical and critical medical devices, respectively – critical medical devices being those with contact to sterile body tissues or fluids – the sterilization procedures do not need to be altered for patients with known or suspected SARS. 7 The probability of microorganism survival is described using the sterility assurance level (SAL), which should be less than 10 −6 for sterilization. Unlike disinfection, sterilization destroys all microorganisms on the surface of an article or in a fluid to prevent disease transmission associated with the use of that item. The application of UV radiation in the healthcare environment (i.e., operating rooms, isolation rooms, and biological safety cabinets) is limited to the destruction of airborne organisms or inactivation of microorganisms on surfaces. Microorganism inactivation is the result of the destruction of nucleic acid through the induction of thymine dimers. 13 Its maximum bactericidal effect occurs at the wavelength range of 240–280 nm. 12 The other method of disinfection is using UV radiation. 11 It has been observed that the SARS coronavirus is inactivated completely by 70% ethanol and povidone-iodine with an exposure time of one minute, and by 2.5% glutaraldehyde with an exposure time of five minutes. Povidone-iodine has been shown to be active against human coronaviruses 229E and OC43. 8 Sodium hypochlorite, ethyl alcohol, 9 isopropanol and benzalkonium chloride 10 are effective against Corona virus. 7 The chemical disinfectants achieve a 5-log reduction of bacterial contaminants in five minutes. The method prescribed by the US Centers for Disease Control and Prevention (CDC) for disinfecting surfaces is to use different chemical disinfectants. 5,6 These facts need to be considered when developing an efficient method for their inactivation. 2–4 They can also be deposited on surfaces, where, depending on the material, they can survive even for several days. Severe acute respiratory syndrome (SARS) viruses are known to be transmitted by inhalable respiratory droplets in aerosols. In this document, we evaluate the potential of piezobrush® PZ3 and piezoelectric direct discharge (PDD) for virus inactivation. ![]() The piezobrush® PZ3, powered by the CeraPlas TM F-type piezoelectric transformer (PT), is used to generate an atmosphere with a high concentration of chemically active species and ions. Piezobrush® PZ3: potential for virus inactivationĪuthors: Dariusz Korzec, Simona Lerach and Stefan Nettesheim Abstract
0 Comments
Leave a Reply. |
Details
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |